John Highton Selected Research

Rheumatoid Nodule

11/2017	Expression of the genes facilitating methotrexate action within subcutaneous rheumatoid nodules.
6/2008	Different T cell subsets in the nodule and synovial membrane: absence of interleukin-17A in rheumatoid nodules.
2/2003	Cytokine profile of the rheumatoid nodule suggests that it is a Th1 granuloma.

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John Highton Research Topics

Disease

12	Rheumatoid Arthritis 01/2018 - 02/2003
6	Inflammation (Inflammations) 01/2018 - 06/2008
5	Ankylosing Spondylitis 01/2018 - 04/2009
4	Gout 12/2014 - 11/2009
3	Rheumatoid Nodule 11/2017 - 02/2003
2	Giant Cell Arteritis (Horton Disease) 09/2017 - 02/2017
2	Fatigue 01/2014 - 10/2010
2	Pain (Aches) 10/2010 - 02/2010
2	Polymyositis 02/2010 - 02/2006
2	Synovitis 03/2008 - 01/2005
1	Tertiary Lymphoid Structures 01/2018
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2018
1	Muscular Diseases (Myopathy) 01/2018
1	Crohn Disease (Crohn's Disease) 01/2018
1	Coronary Artery Disease (Coronary Atherosclerosis) 09/2017
1	Genetic Predisposition to Disease (Genetic Predisposition) 10/2013
1	Pneumonia (Pneumonitis) 10/2011
1	Lung Diseases (Lung Disease) 10/2011
1	Myositis (Idiopathic Inflammatory Myopathies) 02/2010
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2009
1	Osteoporosis 03/2008
1	Joint Diseases (Joint Disease) 03/2008
1	Arthritis (Polyarthritis) 03/2008
1	Osteolysis 10/2007
1	Segmental glomerulosclerosis 10/2007
1	Carpal Tunnel Syndrome 01/2005
1	Granuloma 02/2003

Drug/Important Bio-Agent (IBA)

3	Uric Acid (Urate)IBA 12/2014 - 12/2010
3	Interleukin-17 (Interleukin 17)IBA 10/2012 - 06/2008
2	Methotrexate (Mexate)FDA LinkGeneric 11/2017 - 10/2011
2	Pharmaceutical PreparationsIBA 09/2017 - 10/2011
2	HLA-B27 Antigen (HLA B27 Antigen)IBA 01/2014 - 10/2013
2	urate transporterIBA 04/2012 - 11/2009
2	RNA (Ribonucleic Acid)IBA 11/2009 - 06/2008
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2018
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018
1	SteroidsIBA 02/2017
1	Anticonvulsants (Antiepileptic Drugs)IBA 02/2017
1	MonosaccharidesIBA 12/2014
1	SugarsIBA 12/2014
1	High Fructose Corn SyrupIBA 12/2014
1	FructoseIBA 12/2014
1	Glucose (Dextrose)FDA LinkGeneric 12/2014
1	Sucrose (Saccharose)IBA 12/2014
1	AntigensIBA 01/2014
1	HLA-B*27:05 antigenIBA 10/2013
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 06/2012
1	Interleukin-23 (Interleukin 23)IBA 01/2012
1	Protein Isoforms (Isoforms)IBA 02/2011
1	C-Reactive ProteinIBA 10/2010
1	Antigen-Antibody Complex (Immune Complex)IBA 09/2010
1	DNA (Deoxyribonucleic Acid)IBA 02/2010
1	HLA Antigens (Human Leukocyte Antigens)IBA 02/2010
1	ametantrone (HAQ)IBA 02/2010
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 02/2010
1	P-2 (P 2)IBA 01/2010
1	InterleukinsIBA 11/2009
1	Interleukin-10 (Interleukin 10)IBA 04/2009
1	Antirheumatic Agents (DMARD)IBA 05/2008
1	Biological ProductsIBA 05/2008
1	Alendronate (Alendronate Sodium)FDA LinkGeneric 03/2008
1	diphosphoric acid (pyrophosphoric acid)IBA 03/2008
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 10/2007
1	FibrinIBA 02/2006
1	AcidsIBA 01/2005
1	Interleukin-12 (IL 12)IBA 02/2003
1	CytokinesIBA 02/2003
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2003

Therapy/Procedure

2	Therapeutics 11/2017 - 09/2017
1	Biological Therapy 01/2018
1	Drug-Eluting Stents 09/2017
1	Stents 09/2017
1	Patient Discharge 10/2011